CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:EMD 1201081
Synonyms:IMO-2055
Drug Status For Certain Diseases:Renal cell carcinoma;Solid Tumours(phase II)
Classification:a novel TLR9 agonist with potential to enhance the antitumor efficacy of biologics and small molecules through immune stimulation
Target:Toll-like receptor 9
KEGG Pathway:Measles
Malaria
Tuberculosis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Herpes simplex infection
Toll-like receptor signaling pathway
Wiki Pathway:Trafficking and processing of endosomal TLR
MyD88 dependent cascade initiated on endosome
Toll-like receptor signaling pathway
Regulation of toll-like receptor signaling pathway
Toll-Like Receptors Cascades
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)