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| Agent Info | |
| Agent: | INC280 |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | solid tumours(phase II) |
| Classification: | a highly selective, oral small molecule MET inhibitor with preclinical activity in human tumor models. |
| Target: | Hepatocyte growth factor receptor |
| KEGG Pathway: | Ras signaling pathway Renal cell carcinoma Central carbon metabolism in cancer MicroRNAs in cancer Proteoglycans in cancer Transcriptional misregulation in cancer Epithelial cell signaling in Helicobacter pylori infection Cytokine-cytokine receptor interaction Pathways in cancer PI3K-Akt signaling pathway Rap1 signaling pathway Endocytosis Bacterial invasion of epithelial cells Axon guidance Melanoma Adherens junction Focal adhesion |
| Wiki Pathway: | miR-targeted genes in muscle cell - TarBase Extracellular vesicle-mediated signaling in recipient cells miR-targeted genes in squamous cell - TarBase TGF beta Signaling Pathway miR-targeted genes in lymphocytes - TarBase Signaling Pathways in Glioblastoma Semaphorin interactions miR-targeted genes in epithelium - TarBase Focal Adhesion Signaling of Hepatocyte Growth Factor Receptor |