View Agent
| Agent Info | |
| Agent: | PF299804 |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | NA |
| Classification: | a potent, orally available, irreversible inhibitor of tyrosine kinase human epidermal growth factor receptors (HER) 1 (EGFR), human epidermal growth factor receptor 2, and HER4. |
| Target: | epidermal growth factor receptors (HER) 1 (EGFR) human epidermal growth factor receptor 2 and HER4 |
| KEGG Pathway: | Pancreatic cancer non-small-cell lung cancer Adherens junction HIF-1 signaling pathway Prostate cancer Central carbon metabolism in cancer Focal adhesion MicroRNAs in cancer Pathways in cancer Calcium signaling pathway ErbB signaling pathway Bladder cancer Endometrial cancer |
| Wiki Pathway: | Leptin signaling pathway Signaling by ERBB2 Signaling Pathways in Glioblastoma EGF/EGFR Signaling Pathway Semaphorin interactions miR-targeted genes in muscle cell - TarBase ErbB Signaling Pathway Extracellular vesicle-mediated signaling in recipient cells Focal Adhesion Bladder Cancer DNA Damage Response (only ATM dependent) Integrated Pancreatic Cancer Pathway |