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| Agent Info | |
| Agent: | PTK787/ZK 222584 |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | Glioma;Solid tumours;non-small-cell lung cancer …(phase II) |
| Classification: | an oral inhibitor of VEGFR1 (Flt-1), VEGFR2 (KDR) and VEGFR3 (Flt-4) |
| Target: | Vascular endothelial growth factor receptor 2 |
| KEGG Pathway: | PI3K-Akt signaling pathway Endocytosis VEGF signaling pathway Rap1 signaling pathway Ras signaling pathway |
| Wiki Pathway: | Nifedipine Activity Angiogenesis Focal Adhesion Signaling by VEGF Cardiac Progenitor Differentiation |