View Agent
| Agent Info | |
| Agent: | ZK 304709 |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | Advanced solid tumours(Discontinued inphase 1) |
| Classification: | a novel multi-targeted growth inhibitor (MTGI) with activity against cell-cycle progression and angiogenesis |
| Target: | Cell division protein kinase 4 Cell division control protein 2 homolog Cell division protein kinase 9 Cell division protein kinase 7 Cell division protein kinase 2 |
| KEGG Pathway: | Progesterone-mediated oocyte maturation non-small-cell lung cancer Gap junction Pathways in cancer Small cell lung cancer Bladder cancer Cell cycle Tight junction Glioma Chronic myeloid leukemia Melanoma Pancreatic cancer Oocyte meiosis Prostate cancer |
| Wiki Pathway: | DNA Damage Response TGF beta Signaling Pathway Aryl Hydrocarbon Receptor Integrated Pancreatic Cancer Pathway TSH signaling pathway Cell Cycle Checkpoints miRNA Regulation of DNA Damage Response MicroRNAs in cardiomyocyte hypertrophy IL-9 Signaling Pathway Mitotic Prophase Retinoblastoma (RB) in Cancer Regulation of Microtubule Cytoskeleton DNA Replication Meiotic Recombination Integrated Breast Cancer Pathway Integrated Cancer pathway Mitotic G2-G2/Mphases HIV Life Cycle Host Interactions of HIV factors PPAR Alpha Pathway BMI1 Oncostatin M Signaling Pathway Signaling Pathways in Glioblastoma Factors involved in megakaryocyte development and platelet production mRNA Capping Transcriptional Regulation of White Adipocyte Differentiation MAP kinase activation in TLR cascade RAF/MAP kinase cascade ID signaling pathway Mitotic G1-G1/Sphases RNA Polymerase II Transcription Mitotic Prometaphase Transcriptional activity of SMAD2/SMAD3 Ovarian Infertility Genes Bladder Cancer G1 to S cell cycle control Sphase Prostate Cancer Synthesis of DNA ATM Signaling Pathway Spinal Cord Injury Regulation of DNA replication Cell Cycle APC/C-mediated degradation of cell cycle proteins Eukaryotic Transcription Initiation Cardiac Hypertrophic Response Nucleotide Excision Repair RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription M/G1 Transition |