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| Agent Info | |
| Agent: | abituzumab |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | Colorectal cancer(phase II) |
| Classification: | a humanised monoclonal antibody targeting integrin αν heterodimers |
| Target: | Integrin alpha-V |
| KEGG Pathway: | Hypertrophic cardiomyopathy (HCM) Small cell lung cancer Dilated cardiomyopathy Pathways in cancer Cell adhesion molecules (CAMs) Phagosome Arrhythmogenic right ventricular cardiomyopathy (ARVC) Thyroid hormone signaling pathway ECM-receptor interaction Focal adhesion Proteoglycans in cancer Regulation of actin cytoskeleton |
| Wiki Pathway: | Osteoblast Signaling Focal Adhesion Arrhythmogenic Right Ventricular Cardiomyopathy Syndecan interactions Integrin cell surface interactions Osteopontin Signaling Cell surface interactions at the vascular wall Elastic fibre formation L1CAM interactions Primary Focal Segmental Glomerulosclerosis FSGS Extracellular matrix organization Class I MHC mediated antigen processing & presentation Integrin-mediated Cell Adhesion |