CMTTdb

An integrated database for cancer molecular targeted thearpies

View Agent


Agent Info
Agent:alectinib
Synonyms:CH5424802/RO5424802
Drug Status For Certain Diseases:NA
Classification:2nd-generation,novel, highly selective, and potent ALK inhibitor that has shown clinical activity in patients with crizotinib-naive ALK-rearranged non-small-cell lung cancer
Target:ALK
L1196M
G1269A
C1156Y
F1174L
KEGG Pathway:MAPK pathway
PI3K-AKT pathway
JAK-STAT pathway
Wiki Pathway:NA