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| Agent Info | |
| Agent: | axitinib |
| Synonyms: | AG 013736;AG013736;AG-013736;AG-13736;AG-013736, Axitinib;N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide;N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide |
| Drug Status For Certain Diseases: | Approved(Advanced renal cell carcinoma ) |
| Classification: | an oral receptor tyrosine kinase inhibitor of vascular endothelial cell growth factor, platelet-derived growth factor, and c-Kit |
| Target: | Macrophage colony-stimulating factor 1 Vascular endothelial growth factor receptor 2 Platelet-derived growth factor receptor |
| KEGG Pathway: | PI3K-Akt signaling pathway TNF signaling pathway Ras signaling pathway Rheumatoid arthritis Hematopoietic cell lineage VEGF signaling pathway Rap1 signaling pathway Osteoclast differentiation Cytokine-cytokine receptor interaction Endocytosis |
| Wiki Pathway: | Nifedipine Activity Focal Adhesion Signaling by VEGF Differentiation Pathway miR-targeted genes in muscle cell - TarBase Cardiac Progenitor Differentiation Cytokines and Inflammatory Response Angiogenesis Folate Metabolism Hematopoietic Stem Cell Differentiation |