View Agent
| Agent Info | |
| Agent: | bevacizumab |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | approved |
| Classification: | a recombinant humanized version of a murine antihuman VEGF monoclonal antibody Dual blockade of tumor angiogenesis and EGFR signaling could theoretically result in better antitumor efficacy by targeting both tumor neovascularization and cancer cells |
| Target: | Vascular endothelial growth factor Epidermal growth factor receptor |
| KEGG Pathway: | MicroRNAs in cancer ErbB signaling pathway HIF-1 signaling pathway non-small-cell lung cancer Focal adhesion Calcium signaling pathway Endometrial cancer Pathways in cancer Central carbon metabolism in cancer Bladder cancer Adherens junction Pancreatic cancer Prostate cancer |
| Wiki Pathway: | Integrated Pancreatic Cancer Pathway DNA Damage Response (only ATM dependent) Focal Adhesion Extracellular vesicle-mediated signaling in recipient cells Semaphorin interactions EGF/EGFR Signaling Pathway Leptin signaling pathway Signaling Pathways in Glioblastoma Bladder Cancer Signaling by ERBB2 miR-targeted genes in muscle cell - TarBase ErbB Signaling Pathway |