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Agent Info | |
Agent: | brivanib |
Synonyms: | Brivanib alaninate;BMS 582664;BMS582664;BMS-582664, Brivanib alaninate;Brivanib alaninate (INN/USAN);L-Alanine, (1R)-2-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yl)oxy)-1-methylethyl ester |
Drug Status For Certain Diseases: | Hepatocellular carcinoma(phase III) |
Classification: | a dual inhibitor of vascular-endothelial growth factor and fibroblast growth factor receptors that are implicated in the pathogenesis of hepatocellular carcinoma (hepatocellular carcinoma). |
Target: | vascular-endothelial growth factor fibroblast growth factor receptors |
KEGG Pathway: | Bladder cancer Endocytosis Central carbon metabolism in cancer Pathways in cancer Rap1 signaling pathway Ras signaling pathway MicroRNAs in cancer Signaling pathways regulating pluripotency of stem cells Regulation of actin cytoskeleton PI3K-Akt signaling pathway MAPK signaling pathway |
Wiki Pathway: | Regulation of Actin Cytoskeleton Neural Crest Differentiation Endochondral Ossification Signaling by FGFR Bladder Cancer |