CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:brivanib
Synonyms:Brivanib alaninate;BMS 582664;BMS582664;BMS-582664, Brivanib alaninate;Brivanib alaninate (INN/USAN);L-Alanine, (1R)-2-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yl)oxy)-1-methylethyl ester
Drug Status For Certain Diseases:Hepatocellular carcinoma(phase III)
Classification:a dual inhibitor of vascular-endothelial growth factor and fibroblast growth factor receptors that are implicated in the pathogenesis of hepatocellular carcinoma (hepatocellular carcinoma).
Target:vascular-endothelial growth factor
fibroblast growth factor receptors
KEGG Pathway:Bladder cancer
Endocytosis
Central carbon metabolism in cancer
Pathways in cancer
Rap1 signaling pathway
Ras signaling pathway
MicroRNAs in cancer
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
PI3K-Akt signaling pathway
MAPK signaling pathway
Wiki Pathway:Regulation of Actin Cytoskeleton
Neural Crest Differentiation
Endochondral Ossification
Signaling by FGFR
Bladder Cancer