CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:cediranib
Synonyms:Recentin;AZD 2171;AZD2171;M6294;AZD-2171;ZD-2171;AZD2171, Recentin, Cediranib;Cediranib (USAN/INN);4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline;4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline
Drug Status For Certain Diseases:phase III(Fallopian tube cancer;Ovarian cancer;Peritoneal cavity cancer )
Classification:a potent inhibitor of vascular endothelial growth factor receptors
Target:Vascular endothelial growth factor receptor 2
KEGG Pathway:PI3K-Akt signaling pathway
VEGF signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
Wiki Pathway:Angiogenesis
Signaling by VEGF
Nifedipine Activity
Focal Adhesion
Cardiac Progenitor Differentiation