View Agent
| Agent Info | |
| Agent: | cetuximab |
| Synonyms: | Erbitux;Cetuximab (genetical recombination);Erbitux (TN);Cetuximab (USAN/INN);Cetuximab (genetical recombination) (JAN) |
| Drug Status For Certain Diseases: | Colorectal cancer(approved) |
| Classification: | a chimeric IgG1 monoclonal antibody that binds to EGFR with high specificity and with a higher affinity than either epidermal growth factor or TGF-α, thus blocking ligand-induced phosphorylation of EGFR. |
| Target: | Epidermal growth factor receptor |
| KEGG Pathway: | NA |
| Wiki Pathway: | Hair Follicle Development PIP3 activates AKT signaling Aryl Hydrocarbon Receptor Gastric cancer network 2 miR-targeted genes in muscle cell - TarBase EGF/EGFR Signaling Pathway Extracellular vesicle-mediated signaling in recipient cells Nanoparticle-mediated activation of receptor signaling Spinal Cord Injury Signaling Pathways in Glioblastoma MAPK Signaling Pathway Focal Adhesion TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer Signaling by ERBB2 Integrated Breast Cancer Pathway Arylhydrocarbon receptor (AhR) signaling pathway Signaling by ERBB4 ErbB Signaling Pathway Integrated Pancreatic Cancer Pathway Aryl Hydrocarbon Receptor Pathway Regulation of Actin Cytoskeleton Signaling by EGFR miR-targeted genes in epithelium - TarBase miR-targeted genes in lymphocytes - TarBase Hair Follicle Development Bladder Cancer Gastrin-CREB signalling pathway via PKC and MAPK AGE/RAGE pathway L1CAM interactions |