CMTTdb

An integrated database for cancer molecular targeted thearpies

View Agent


Agent Info
Agent:custirsen
Synonyms:OGX-011/TV-1011
Drug Status For Certain Diseases:cancer(phase III),prostate cancer(phase III)
Classification: a second-generation phosphorothioate antisense that is complementary to the clusterin mRNA translation initiation site. It potently inhibits clusterin expression and enhances the efficacy of anticancer therapies in vitro and in vivo.
Target:Clusterin (CLU)
KEGG Pathway:NA
Wiki Pathway:NA