View Agent
| Agent Info | |
| Agent: | dabrafenib |
| Synonyms: | GSK2118436 |
| Drug Status For Certain Diseases: | Metastatic or unresectable malignant melanoma with BRAF V600E or V600K mutation(approved) |
| Classification: | a selective BRAF inhibitor |
| Target: | B-Raf proto-oncogene serine/threonine-protein kinase |
| KEGG Pathway: | NA |
| Wiki Pathway: | Corticotropin-releasing hormone Focal Adhesion Serotonin HTR1 Group and FOS Pathway Regulation of Actin Cytoskeleton MAPK Cascade Bladder Cancer Integrin-mediated Cell Adhesion Estrogen signaling pathway Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell TSH signaling pathway EGF/EGFR Signaling Pathway B Cell Receptor Signaling Pathway Integrated Breast Cancer Pathway NGF signalling via TRKA from the plasma membrane Signaling by FGFR Signaling Pathways in Glioblastoma Polycystic Kidney Disease Pathway Serotonin Receptor 4/6/7 and NR3C Signaling MAPK Signaling Pathway Senescence and Autophagy in Cancer |