CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:dacomitinib
Synonyms:PF-00299804
Drug Status For Certain Diseases:Non-small-cell lung carcinoma(phase III)
Classification:2nd-generation,irreversible pan-EGFR family tyrosine kinase inhibitor
Target:Epidermal growth factor receptor
Proto oncogene protein-c mdm2
Erbb2 tyrosine kinase receptor
KEGG Pathway:NA
Wiki Pathway:ErbB Signaling Pathway
Aryl Hydrocarbon Receptor Pathway
Hair Follicle Development
Bladder Cancer
miR-targeted genes in epithelium - TarBase
L1CAM interactions
Hair Follicle Development
Signaling by ERBB2
Gastrin-CREB signalling pathway via PKC and MAPK
Integrated Pancreatic Cancer Pathway
Integrated Breast Cancer Pathway
Aryl Hydrocarbon Receptor
miR-targeted genes in muscle cell - TarBase
MAPK Signaling Pathway
Extracellular vesicle-mediated signaling in recipient cells
Signaling Pathways in Glioblastoma
AGE/RAGE pathway
Signaling by ERBB4
Focal Adhesion
Regulation of Actin Cytoskeleton
TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
Nanoparticle-mediated activation of receptor signaling
PIP3 activates AKT signaling
Arylhydrocarbon receptor (AhR) signaling pathway
Signaling by EGFR
miR-targeted genes in lymphocytes - TarBase
Gastric cancer network 2
Spinal Cord Injury
EGF/EGFR Signaling Pathway