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| Agent Info | |
| Agent: | danusertib |
| Synonyms: | PHA 739358;Danusertib, PHA-739358;(R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide;5-Amido-pyrrolopyrazole 9d |
| Drug Status For Certain Diseases: | prostate cancer(phase II) |
| Classification: | a potent small-molecule 3-aminopyrazole derivative that inhibits all aurora kinases |
| Target: | Aurora kinase A Serine/threonine protein kinase 12 |
| KEGG Pathway: | Oocyte meiosis |
| Wiki Pathway: | miR-targeted genes in epithelium - TarBase miR-targeted genes in lymphocytes - TarBase Gastric Cancer Network 1 APC/C-mediated degradation of cell cycle proteins Mitotic Metaphase and Anaphase JAK/STAT Mitotic Prometaphase Integrated Breast Cancer Pathway EGF/EGFR Signaling Pathway Regulation of Microtubule Cytoskeleton |