CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:ertumaxomab
Synonyms:Rexomab;Rexomun;Trifunctional antibody (breast cancer), TRION/Fresenius;Trifunctional bispecific (CD3/human epidermal growth factor receptor 2/neu) antibody (breast cancer), TRION/Fresenius
Drug Status For Certain Diseases:Breast cancer(phase II)
Classification:trifunctional antibody
Target:Receptor protein-tyrosine kinase erbB-2
T-cell surface glycoprotein CD3 epsilon chain
CD3
KEGG Pathway:ErbB signaling pathway
Bladder cancer
HTLV-I infection
Prostate cancer
Hematopoietic cell lineage
non-small-cell lung cancer
Chagas disease (American trypanosomiasis)
Primary immunodeficiency
Pancreatic cancer
Central carbon metabolism in cancer
Calcium signaling pathway
Pathways in cancer
Endometrial cancer
Adherens junction
Measles
HIF-1 signaling pathway
T cell receptor signaling pathway
Focal adhesion
MicroRNAs in cancer
Wiki Pathway:Leptin signaling pathway
miR-targeted genes in muscle cell - TarBase
Integrated Pancreatic Cancer Pathway
Extracellular vesicle-mediated signaling in recipient cells
DNA Damage Response (only ATM dependent)
TCR signaling
TCR Signaling Pathway
Signaling by ERBB2
Costimulation by the CD28 family
Fcgamma receptor (FCGR) dependent phagocytosis
Focal Adhesion
Signaling Pathways in Glioblastoma
Bladder Cancer
EGF/EGFR Signaling Pathway
Immunoregulatory interactions bettheyen a Lymphoid and a non-Lymphoid cell
ErbB Signaling Pathway
Semaphorin interactions