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| Agent Info | |
| Agent: | ganitumab |
| Synonyms: | AMG 479 |
| Drug Status For Certain Diseases: | Breast cancer(phase II) |
| Classification: | an investigational, fully human, monoclonal antibody antagonist of IGF1R, prevents binding of IGF-1 and IGF-2 to IGF1R |
| Target: | Insulin-like growth factor I receptor |
| KEGG Pathway: | Signaling pathways regulating pluripotency of stem cells Progesterone-mediated oocyte maturation Ras signaling pathway Rap1 signaling pathway Prostate cancer Adherens junction Glioma AMPK signaling pathway PI3K-Akt signaling pathway Focal adhesion Pathways in cancer Endocytosis Melanoma HIF-1 signaling pathway Oocyte meiosis Proteoglycans in cancer Ovarian steroidogenesis FoxO signaling pathway |
| Wiki Pathway: | Apoptosis Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Focal Adhesion Senescence and Autophagy in Cancer Insulin Signaling MicroRNAs in cardiomyocyte hypertrophy Endochondral Ossification Signaling Pathways in Glioblastoma TSH signaling pathway |