CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:iniparib
Synonyms:BSI-201
Drug Status For Certain Diseases:Solid tumours(phase III)
Classification:a novel anticancer agent initially considered a poly (ADP-ribose) polymerase (PARP) inhibitor, but subsequently shown to act via non-selective protein modification through cysteine adducts
Target:Poly [ADP-ribose] polymerase-1
KEGG Pathway:NA
Wiki Pathway:Transcriptional activity of SMAD2/SMAD3
Corticotropin-releasing hormone
Nanoparticle triggered regulated necrosis
FAS pathway and Stress induction of HSP regulation