View Agent
| Agent Info | |
| Agent: | ipilimumab |
| Synonyms: | BMS-734016;MDX-010;MDX-101;Yervoy (TN) |
| Drug Status For Certain Diseases: | Late-stage melanoma,Prostate cancer(approved) |
| Classification: | a fully human monoclonal antibody (IgG1) that blocks CTLA-4 to promote antitumor immunity |
| Target: | Cytotoxic T-lymphocyte antigen 4 (CTLA-4) |
| KEGG Pathway: | Cell adhesion molecules (CAMs) Autoimmune thyroid disease T cell receptor signaling pathway Rheumatoid arthritis |
| Wiki Pathway: | Allograft Rejection T-Cell Receptor and Co-stimulatory Signaling Vitamin D Receptor Pathway Costimulation by the CD28 family |