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| Agent Info | |
| Agent: | linifanib |
| Synonyms: | Linifanib;ABT 869;S1003_Selleck;AL-39324;RG-3635;ABT869, Linifanib, AL-39324, RG3635;N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea;N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea |
| Drug Status For Certain Diseases: | Solid tumours(phase III) |
| Classification: | a potent, selective inhibitor of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors |
| Target: | Macrophage colony-stimulating factor 1 |
| KEGG Pathway: | Hematopoietic cell lineage Cytokine-cytokine receptor interaction Ras signaling pathway TNF signaling pathway Rheumatoid arthritis Rap1 signaling pathway PI3K-Akt signaling pathway Osteoclast differentiation |
| Wiki Pathway: | Hematopoietic Stem Cell Differentiation Cytokines and Inflammatory Response miR-targeted genes in muscle cell - TarBase Folate Metabolism Differentiation Pathway |