View Agent
| Agent Info | |
| Agent: | oblimersen sodium |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | Advanced Melanoma;Multiple myeloma …(phase III) |
| Classification: | a fully phosphorothioated antisense oligonucleotide that selectively down-regulates Bcl-2 protein expression. |
| Target: | Apoptosis regulator Bcl-2 |
| KEGG Pathway: | Pathways in cancer Hepatitis B Tuberculosis MicroRNAs in cancer Epstein-Barr virus infection Sphingolipid signaling pathway Colorectal cancer Amyotrophic lateral sclerosis (ALS) Prostate cancer Toxoplasmosis PI3K-Akt signaling pathway Apoptosis Small cell lung cancer HIF-1 signaling pathway Protein processing in endoplasmic reticulum |
| Wiki Pathway: | FAS pathway and Stress induction of HSP regulation TP53 Network Influenza A virus infection IL-3 Signaling Pathway Apoptosis Kit receptor signaling pathway Amyotrophic lateral sclerosis (ALS) Corticotropin-releasing hormone Prostate Cancer Apoptosis Modulation and Signaling IL-2 Signaling Pathway Interleukin-11 Signaling Pathway miR-targeted genes in lymphocytes - TarBase Focal Adhesion Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Senescence and Autophagy in Cancer miR-targeted genes in muscle cell - TarBase IL-5 Signaling Pathway DNA Damage Response (only ATM dependent) Integrated Pancreatic Cancer Pathway miR-targeted genes in leukocytes - TarBase Integrated Breast Cancer Pathway Intrinsic Pathway for Apoptosis Integrated Cancer pathway Nanoparticle triggered autophagic cell death |