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| Agent Info | |
| Agent: | olaparib |
| Synonyms: | AZD 2281;AZD2281;AZD-2281;Acylpiperazine analogue, 47;KU-0059436;KU-59436;Olaparib, KU-0059436, AZD2281, KU0059436, AZD2281;4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one;4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
| Drug Status For Certain Diseases: | Breast cancer;Ovarian cancer(phase III) |
| Classification: | an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2) -associated breast and ovarian cancers |
| Target: | Poly [ADP-ribose] polymerase-1 |
| KEGG Pathway: | NA |
| Wiki Pathway: | Nanoparticle triggered regulated necrosis Corticotropin-releasing hormone FAS pathway and Stress induction of HSP regulation Transcriptional activity of SMAD2/SMAD3 |