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| Agent Info | |
| Agent: | palbociclib |
| Synonyms: | Ibrance;Cell cycle regulators, Pfizer;PD-0205606;PD-0332991;PD-332991;PF-332991;Cell cycle regulators, Onyx/Pfizer;Cell cycle regulators, Onyx/Parke-Davis |
| Drug Status For Certain Diseases: | Metastatic HER2-negative, ER-positive breast cancer in postmenopausal women in combination with letrozole (approved) |
| Classification: | an inhibitor of CDK4 and CDK6 |
| Target: | Cell division protein kinase 6 Cell division protein kinase 4 |
| KEGG Pathway: | Glioma MicroRNAs in cancer Chronic myeloid leukemia Bladder cancer Small cell lung cancer Cell cycle Pancreatic cancer Melanoma non-small-cell lung cancer Tight junction Pathways in cancer |
| Wiki Pathway: | miRNAs involved in DNA damage response Spinal Cord Injury G1 to S cell cycle control Retinoblastoma (RB) in Cancer Signaling Pathways in Glioblastoma Integrated Breast Cancer Pathway Integrated Cancer pathway miRNA Regulation of DNA Damage Response Bladder Cancer Integrated Pancreatic Cancer Pathway Metastatic brain tumor PPAR Alpha Pathway Sphase Meiotic Recombination Transcriptional Regulation of White Adipocyte Differentiation Ovarian Infertility Genes DNA Damage Response miR-targeted genes in muscle cell - TarBase Wnt Signaling Pathway Netpath TSH signaling pathway Prostate Cancer miR-targeted genes in lymphocytes - TarBase Cell Cycle miR-targeted genes in epithelium - TarBase Mitotic G1-G1/Sphases miR-targeted genes in leukocytes - TarBase |