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Agent Info | |
Agent: | ramucirumab |
Synonyms: | IMC-1121B, LY3009806 |
Drug Status For Certain Diseases: | Gastric cancer …(Approved) |
Classification: | a recombinant IgG1 monoclonal antibody and VEGF receptor-2 antagonist |
Target: | Vascular endothelial growth factor receptor 2 |
KEGG Pathway: | Rap1 signaling pathway Endocytosis VEGF signaling pathway Ras signaling pathway PI3K-Akt signaling pathway |
Wiki Pathway: | Cardiac Progenitor Differentiation Angiogenesis Focal Adhesion Signaling by VEGF Nifedipine Activity |