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Agent Info | |
Agent: | selumetinib |
Synonyms: | AZD6244;ARRY 142886;ARRY142886;AZD 6244;ARRY-142886;ARRY-886;AZD-6244;ARRY-142886, Selumetinib, AZD-6244, ARRY142886, AZD6244 |
Drug Status For Certain Diseases: | non-small-cell lung cancer;Melanoma(phase II) |
Classification: | an inhibitor of MEK1/MEK2, downstream of KRAS |
Target: | Dual specificity mitogen-activated protein kinase kinase |
KEGG Pathway: | Mitogen-activated protein (MAP) kinase pathway |
Wiki Pathway: | Mitogen-activated protein (MAP) kinase pathway |