CMTTdb

An integrated database for cancer molecular targeted thearpies

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Agent Info
Agent:selumetinib
Synonyms:AZD6244;ARRY 142886;ARRY142886;AZD 6244;ARRY-142886;ARRY-886;AZD-6244;ARRY-142886, Selumetinib, AZD-6244, ARRY142886, AZD6244
Drug Status For Certain Diseases:non-small-cell lung cancer;Melanoma(phase II)
Classification:an inhibitor of MEK1/MEK2, downstream of KRAS
Target:Dual specificity mitogen-activated protein kinase kinase
KEGG Pathway:Mitogen-activated protein (MAP) kinase pathway
Wiki Pathway:Mitogen-activated protein (MAP) kinase pathway