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| Agent Info | |
| Agent: | tivozanib |
| Synonyms: | ASP4130/AV-951 |
| Drug Status For Certain Diseases: | Renal cancer(phase III) |
| Classification: | a potent and selective inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine kinases |
| Target: | VEGF-2 receptor Vascular endothelial growth factor receptor 3 Vascular endothelial growth factor receptor 1 |
| KEGG Pathway: | Rheumatoid arthritis Endocytosis Rap1 signaling pathway Transcriptional misregulation in cancer Ras signaling pathway PI3K-Akt signaling pathway |
| Wiki Pathway: | Angiogenesis Signaling by VEGF Focal Adhesion |