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| Agent Info | |
| Agent: | trebananib |
| Synonyms: | AMG 386 |
| Drug Status For Certain Diseases: | phase III(breast cancer) |
| Classification: | an investigational peptibody that neutralizes the interaction bettheyen angiopoietins-1 and -2 and the Tie2 receptor |
| Target: | Angiopoietin-2 Angiopoietin-1 |
| KEGG Pathway: | Rheumatoid arthritis PI3K-Akt signaling pathway HIF-1 signaling pathway |
| Wiki Pathway: | Cell surface interactions at the vascular wall Angiogenesis |