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| Agent Info | |
| Agent: | tremelimumab |
| Synonyms: | NA |
| Drug Status For Certain Diseases: | solid tumors(phase III) |
| Classification: | a monoclonal antibody that blocks cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), an inhibitory co-receptor that interferes with T cell activation and proliferation. The purpose of this pilot clinical trial was to test the antitumor and antiviral effect of tremelimumab in patients with hepatocellular carcinoma (hepatocellular carcinoma) and chronic hepatitis C virus (HCV) infection |
| Target: | cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) |
| KEGG Pathway: | Autoimmune thyroid disease Cell adhesion molecules (CAMs) Rheumatoid arthritis T cell receptor signaling pathway |
| Wiki Pathway: | Costimulation by the CD28 family Vitamin D Receptor Pathway T-Cell Receptor and Co-stimulatory Signaling Allograft Rejection |