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| Agent Info | |
| Agent: | vemurafenib |
| Synonyms: | PLX4032;RG7204;RO5185426;Zelboraf (TN) |
| Drug Status For Certain Diseases: | Unresectable or metastatic malignant melanoma with BRAF V600E mutation(approved) |
| Classification: | an oral kinase inhibitor specific to mutated V600 BRAF |
| Target: | B-Raf proto-oncogene serine/threonine-protein kinase |
| KEGG Pathway: | NA |
| Wiki Pathway: | TSH signaling pathway B Cell Receptor Signaling Pathway Corticotropin-releasing hormone Bladder Cancer Serotonin HTR1 Group and FOS Pathway EGF/EGFR Signaling Pathway MAPK Cascade NGF signalling via TRKA from the plasma membrane Polycystic Kidney Disease Pathway MAPK Signaling Pathway Regulation of Actin Cytoskeleton Integrin-mediated Cell Adhesion Integrated Breast Cancer Pathway Focal Adhesion Signaling Pathways in Glioblastoma Senescence and Autophagy in Cancer Signaling by FGFR Estrogen signaling pathway Serotonin Receptor 4/6/7 and NR3C Signaling Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell |