ctcRbase

Entry Detail

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General Information

Database ID: BRCA00186 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ACTG1 Full Name: actin gamma 1 Category: mRNA Synonyms: ACT|ACTG|DFNA20|DFNA26|HEL-176 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 81509971 End Site(bp): 81523847 Gene Summary: Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017] External Links: Ensembl ID: ENSG00000184009 HGNC ID: HGNC:144 Entrez Gene: 71

Expression Profile of ACTG1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO YES hsa-miR-107 YES NO YES hsa-miR-10a-5p YES NO YES hsa-miR-10b-5p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-300 YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-411-5p YES YES NO Display: