Entry Detail



General Information

Database ID:BRCA00195
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:PPIA
Full Name:peptidylprolyl isomerase A
Category:mRNA
Synonyms:CYPA|CYPH|HEL-S-69p
Chromosome:chr7
Strand:+
Coordinate:
Start Site(bp):44796680End Site(bp):44824564
Gene Summary:This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000196262
HGNC ID:HGNC:9253
Entrez Gene:5478



Expression Profile of PPIA Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-149-5p
YES
YES
NO
hsa-miR-192-5p
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-215-5p
YES
YES
NO
hsa-miR-219a-5p
YES
YES
NO
hsa-miR-329-3p
YES
YES
NO
hsa-miR-342-3p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-98-5p
YES
YES
NO
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