ctcRbase

Entry Detail

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General Information

Database ID: BRCA00225 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: LDHA Full Name: lactate dehydrogenase A Category: mRNA Synonyms: GSD11|HEL-S-133P|LDHM|PIG19 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 18394388 End Site(bp): 18408425 Gene Summary: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008] External Links: Ensembl ID: ENSG00000134333 HGNC ID: HGNC:6535 Entrez Gene: 3939

Expression Profile of LDHA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-383-5p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES hsa-miR-7-5p YES YES NO hsa-miR-876-5p YES NO YES Display: