ctcRbase

Entry Detail

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General Information

Database ID: BRCA00252 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DDX5 Full Name: DEAD-box helicase 5 Category: mRNA Synonyms: G17P1|HLR1|HUMP68|p68 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 64499616 End Site(bp): 64508199 Gene Summary: This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017] External Links: Ensembl ID: ENSG00000108654 HGNC ID: HGNC:2746 Entrez Gene: 1655

Expression Profile of DDX5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-340-5p YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-613 YES YES YES hsa-miR-758-3p YES YES YES hsa-miR-873-5p YES YES YES hsa-miR-93-5p YES YES YES Display: