ctcRbase

Entry Detail

---



General Information

Database ID: BRCA00288 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: SPARC Full Name: secreted protein acidic and cysteine rich Category: mRNA Synonyms: BM-40|OI17|ON Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 151661096 End Site(bp): 151687165 Gene Summary: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015] External Links: Ensembl ID: ENSG00000113140 HGNC ID: HGNC:11219 Entrez Gene: 6678

Expression Profile of SPARC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-147a YES NO NO hsa-miR-150-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-204-5p YES NO YES hsa-miR-211-5p YES NO YES hsa-miR-224-5p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-31-5p YES YES YES hsa-miR-362-5p YES NO YES hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-455-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-599 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-758-3p YES YES NO hsa-miR-873-5p YES YES NO Display: