ctcRbase

Entry Detail

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General Information

Database ID: BRCA00290 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: TPM4 Full Name: tropomyosin 4 Category: mRNA Synonyms: HEL-S-108 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 16067021 End Site(bp): 16103005 Gene Summary: This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009] External Links: Ensembl ID: ENSG00000167460 HGNC ID: HGNC:12013 Entrez Gene: 7171

Expression Profile of TPM4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p NO YES YES hsa-miR-133b NO YES YES hsa-miR-138-5p YES YES NO hsa-miR-1-3p NO YES YES hsa-miR-142-3p NO YES YES hsa-miR-145-5p NO YES YES hsa-miR-154-5p YES YES NO hsa-miR-206 NO YES YES hsa-miR-216b-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-613 NO YES YES Display: