ctcRbase

Entry Detail

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General Information

Database ID: BRCA00310 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: NRGN Full Name: neurogranin Category: mRNA Synonyms: RC3|hng Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 124739846 End Site(bp): 124747210 Gene Summary: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000154146 HGNC ID: HGNC:8000 Entrez Gene: 4900

Expression Profile of NRGN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-383-5p YES YES NO Display: