ctcRbase

Entry Detail

---



General Information

Database ID: BRCA00377 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PPIA Full Name: peptidylprolyl isomerase A Category: mRNA Synonyms: CYPA|CYPH|HEL-S-69p Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 44796680 End Site(bp): 44824564 Gene Summary: This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000196262 HGNC ID: HGNC:9253 Entrez Gene: 5478

Expression Profile of PPIA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-219a-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-98-5p YES YES NO Display: