ctcRbase

Entry Detail

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General Information

Database ID: BRCA00416 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: RPL28 Full Name: ribosomal protein L28 Category: mRNA Synonyms: L28 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 55385345 End Site(bp): 55403250 Gene Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] External Links: Ensembl ID: ENSG00000108107 HGNC ID: HGNC:10330 Entrez Gene: 6158

Expression Profile of RPL28 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES YES hsa-miR-138-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-224-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-599 YES YES NO Display: