ctcRbase

Entry Detail

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General Information

Database ID: BRCA00425 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: ALDOA Full Name: aldolase, fructose-bisphosphate A Category: mRNA Synonyms: ALDA|GSD12|HEL-S-87p Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 30053090 End Site(bp): 30070457 Gene Summary: This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017] External Links: Ensembl ID: ENSG00000149925 HGNC ID: HGNC:414 Entrez Gene: 226

Expression Profile of ALDOA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES YES hsa-miR-1271-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-329-3p YES YES YES hsa-miR-335-5p YES NO YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-362-3p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-96-5p YES YES NO Display: