ctcRbase

Entry Detail

---



General Information

Database ID: BRCA00481 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SOD1 Full Name: superoxide dismutase 1 Category: mRNA Synonyms: ALS|ALS1|HEL-S-44|IPOA|SOD|hSod1|homodimer Chromosome: chr21 Strand: + Coordinate: Start Site(bp): 31659622 End Site(bp): 31668931 Gene Summary: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000142168 HGNC ID: HGNC:11179 Entrez Gene: 6647

Expression Profile of SOD1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-139-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO Display: