ctcRbase

Entry Detail

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General Information

Database ID: BRCA00517 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MYL12A Full Name: myosin light chain 12A Category: mRNA Synonyms: HEL-S-24|MLC-2B|MLCB|MRCL3|MRLC3|MYL2B Chromosome: chr18 Strand: + Coordinate: Start Site(bp): 3247481 End Site(bp): 3256236 Gene Summary: This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014] External Links: Ensembl ID: ENSG00000101608 HGNC ID: HGNC:16701 Entrez Gene: 10627

Expression Profile of MYL12A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-873-5p YES YES NO Display: