ctcRbase

Entry Detail

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General Information

Database ID: BRCA00527 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: H2AFZ Full Name: H2A histone family member Z Category: mRNA Synonyms: H2A.Z-1|H2A.z|H2A/z|H2AZ Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 99948086 End Site(bp): 99950388 Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000164032 HGNC ID: HGNC:4741 Entrez Gene: 3015

Expression Profile of H2AFZ Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-132-3p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-208a-3p YES YES YES hsa-miR-208b-3p YES YES YES hsa-miR-212-3p YES YES YES hsa-miR-215-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-496 YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-505-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-599 YES YES NO Display: