Entry Detail



General Information

Database ID:BRCA00539
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:DSTN
Full Name:destrin, actin depolymerizing factor
Category:mRNA
Synonyms:ACTDP|ADF|HEL32|bA462D18.2
Chromosome:chr20
Strand:+
Coordinate:
Start Site(bp):17569863End Site(bp):17609919
Gene Summary:The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000125868
HGNC ID:HGNC:15750
Entrez Gene:11034



Expression Profile of DSTN Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-136-5p
YES
YES
NO
hsa-miR-153-3p
YES
YES
NO
hsa-miR-186-5p
YES
YES
YES
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-452-5p
YES
NO
YES
hsa-miR-455-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-543
YES
YES
YES
hsa-miR-758-3p
YES
NO
YES
hsa-miR-7-5p
YES
YES
NO
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