ctcRbase

Entry Detail

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General Information

Database ID: BRCA00600 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: SP100 Full Name: SP100 nuclear antigen Category: mRNA Synonyms: lysp100b Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 230415942 End Site(bp): 230544090 Gene Summary: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000067066 HGNC ID: HGNC:11206 Entrez Gene: 6672

Expression Profile of SP100 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-543 YES YES NO Display: