Entry Detail



General Information

Database ID:BRCA00604
Cancer Type:breast cancer
Dataset:GSE75367
CTCs/CTM Isolation Method:micromanipulation immunofluorescence



Gene Information

ncRNA Symbol:SAT1
Full Name:spermidine/spermine N1-acetyltransferase 1
Category:mRNA
Synonyms:DC21|KFSD|KFSDX|SAT|SSAT|SSAT-1
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):23783173End Site(bp):23786226
Gene Summary:The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
External Links:
Ensembl ID:ENSG00000130066
HGNC ID:HGNC:10540
Entrez Gene:6303



Expression Profile of SAT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1-3p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-199a-5p
YES
YES
YES
hsa-miR-199b-5p
YES
YES
YES
hsa-miR-206
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-433-3p
NO
YES
YES
hsa-miR-613
YES
YES
NO
hsa-miR-9-5p
YES
YES
NO
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