ctcRbase

Entry Detail

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General Information

Database ID: BRCA00700 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: PFN1 Full Name: profilin 1 Category: mRNA Synonyms: ALS18 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 4945652 End Site(bp): 4949061 Gene Summary: This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012] External Links: Ensembl ID: ENSG00000108518 HGNC ID: HGNC:8881 Entrez Gene: 5216

Expression Profile of PFN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES NO YES hsa-miR-182-5p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-599 YES YES NO hsa-miR-96-5p YES NO YES Display: