Entry Detail



General Information

Database ID:BRCA00712
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:SQSTM1
Full Name:sequestosome 1
Category:mRNA
Synonyms:A170|DMRV|FTDALS3|NADGP|OSIL|PDB3|ZIP3|p60|p62|p62B
Chromosome:chr5
Strand:+
Coordinate:
Start Site(bp):179806398End Site(bp):179838078
Gene Summary:This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
External Links:
Ensembl ID:ENSG00000161011
HGNC ID:HGNC:11280
Entrez Gene:8878



Expression Profile of SQSTM1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
YES
hsa-miR-106b-5p
YES
YES
YES
hsa-miR-124-3p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
YES
hsa-miR-135b-5p
YES
YES
YES
hsa-miR-139-5p
YES
YES
NO
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
hsa-miR-154-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
YES
hsa-miR-193a-3p
YES
YES
NO
hsa-miR-193b-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
YES
hsa-miR-20b-5p
YES
YES
YES
hsa-miR-302a-3p
YES
YES
YES
hsa-miR-302b-3p
YES
YES
YES
hsa-miR-302c-3p
YES
YES
YES
hsa-miR-302d-3p
YES
YES
YES
hsa-miR-302e
YES
YES
YES
hsa-miR-362-3p
YES
NO
NO
hsa-miR-372-3p
YES
YES
YES
hsa-miR-373-3p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
YES
hsa-miR-520a-3p
YES
YES
YES
hsa-miR-520b
YES
YES
YES
hsa-miR-520c-3p
YES
YES
YES
hsa-miR-520d-3p
YES
YES
YES
hsa-miR-520e
YES
YES
YES
hsa-miR-551a
YES
YES
NO
hsa-miR-551b-3p
YES
YES
NO
hsa-miR-7-5p
YES
YES
NO
hsa-miR-93-5p
YES
YES
YES
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