ctcRbase

Entry Detail

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General Information

Database ID: BRCA00721 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SRSF3 Full Name: serine and arginine rich splicing factor 3 Category: mRNA Synonyms: SFRS3|SRp20 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 36594353 End Site(bp): 36605600 Gene Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010] External Links: Ensembl ID: ENSG00000112081 HGNC ID: HGNC:10785 Entrez Gene: 6428

Expression Profile of SRSF3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-215-5p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-485-5p NO YES YES hsa-miR-486-5p YES YES YES hsa-miR-488-3p NO YES YES hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-599 YES YES NO hsa-miR-613 YES YES YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: