ctcRbase

Entry Detail

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General Information

Database ID: BRCA00723 Cancer Type: breast cancer Dataset: GSE86978 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TLN1 Full Name: talin 1 Category: mRNA Synonyms: ILWEQ|TLN|talin-1 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 35696948 End Site(bp): 35732395 Gene Summary: This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009] External Links: Ensembl ID: ENSG00000137076 HGNC ID: HGNC:11845 Entrez Gene: 7094

Expression Profile of TLN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-369-3p YES NO YES hsa-miR-424-5p YES YES NO hsa-miR-429 YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-491-5p YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-503-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-9-5p YES YES YES hsa-miR-96-5p YES NO YES Display: